Quinoid derivatives of the nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine: activation pathway to amino acid adducts
TOXICOLOGY RESEARCH, 4, 1565-1577 2015
Shrika G. Harjivan , Pedro F. Pinheiro , Inês Sofia Lança Martins , Ana L. Godinho , Riccardo Wanke , P P Santos , Sofia A. Pereira , Frederick A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

Enzymatic bioactivation of the phenolic nevirapine metabolites 2-hydroxy- and 3-hydroxy-nevirapine to quinoid intermediates: Covalent adduct formation with nitrogen-based amino acids
TOXICOLOGY LETTERS, 238, S359-S360 10 2015
S. G. Harjivan , Pedro F. Pinheiro , Inês Sofia Lança Martins , D. A. Novais , R. Wanke , P P Santos , S. A. Pereira , F. A. Beland , M. Matilde Marques , Alexandra Maria Moita Antunes

Oxidation of 2-Hydroxynevirapine, a Phenolic Metabolite of the Anti-HIV Drug Nevirapine: Evidence for an Unusual Pyridine Ring Contraction
MOLECULES, 17, 2616-2627 3 2012
Alexandra Maria Moita Antunes , Muna Sidarus , David A. Novais , Shrika G. Harjivan , P P Santos , João Ferreira da Silva , Frederick A. Beland , M. Matilde Marques

First Crystal Structures of the Antihypertensive Drug Perindopril Erbumine: A Novel Hydrated Form and Polymorphs alpha and beta
CRYSTAL GROWTH \& DESIGN, 11, 3703-3706 9 2011
Vânia André , Luis Cunha-Silva , M. Teresa Duarte , P P Santos

Synthesis and oxidation of 2-hydroxynevirapine, a metabolite of the HIV reverse transcriptase inhibitor nevirapine
ORGANIC \& BIOMOLECULAR CHEMISTRY, 9, 7822-7835 2011
Alexandra Maria Moita Antunes , David A. Novais , João Ferreira da Silva , P P Santos , M. Conceição Oliveira , Frederick A. Beland , M. Matilde Marques

On the Track of New Multicomponent Gabapentin Crystal Forms: Synthon Competition and pH Stability
CRYSTAL GROWTH \& DESIGN, 11, 2325-2334 6 2011
Vânia André , A Fernandes , P P Santos , M. Teresa Duarte

Synthesis and characterization of DNA adducts from the HIV reverse transcriptase inhibitor nevirapine
CHEMICAL RESEARCH IN TOXICOLOGY, 21, 1443-1456 7 2008
Alexandra Maria Moita Antunes , Mariana P. Duarte , P P Santos , Gongalo Gamboa da Costa , Thomas M. Heinze , Frederick A. Beland , M. Matilde Marques